Объявления: Литература

Спецвыпуск Nature 2014 NOBEL PRIZE IN CHEMISTRY

Scientists long believed that optical microscopy would never be able to resolve distances smaller than half the wavelength of light, 0.2 micrometres. The 2014 Nobel Prize in Chemistry has been awarded to three scientists — Eric Betzig, Stefan W. Hell and William E. Moerner — who broke that limit, bringing optical microscopy down to the nanoscale by exploiting the fluorescence or glow of molecules in response to light.

In celebration, NPG is making available a range of articles from its journal archives that capture and reflect their remarkable achievements. Due to their impact and importance the research articles in the Highlights section will be free to access for a month.

HIGHLIGHTS

• Nobel for microscopy that reveals inner world of cells

  Three scientists used fluorescent molecules to defy the limits of conventional optical microscopes.

  Nature (08 October 2014)

• On/off blinking and switching behaviour of single molecules of green fluorescent protein

  Robert M. Dickson, Andrew B. Cubitt, Roger Y. Tsien and W. E. Moerner.

  Nature (24 July 1997)

• Method of the Year 2008

  Nature Methods' Method of the Year 2008 went to super-resolution fluorescence microscopy. This series of articles—and the related movie—showcase how these novel imaging methods came into their own in 2008 and the incredible impact they promised to have in biological research.

  Nature Methods (17 December 2008)

• Eyes on super-resolution

  Advanced imaging techniques have evolved to see beyond the diffraction limit. W. E. Moerner spoke to Nature Photonics about the techniques involved.

  Nature Photonics (01 July 2009)

• Toward fluorescence nanoscopy

  Nanoscale imaging with focused light may be closer than ever.

  Nature Biotechnology (31 October 2003)

LIBRARY

• Super-resolution microscopy at Nature Methods

  We look back at the relationship between Nature Methods and super-resolution microscopy, one of the technologies we have chosen as one of the top ten methods developments in the ten years since the journal published it first issue.

  Nature Methods (29 September 2014)

• Microscopic marvels: The glorious resolution

  2014 Nobel laureate Stefan Hell fought a bitter battle for recognition as he worked to reinvent microscopy as nanoscopy.

  Nature (03 June 2009)

• Super–resolution imaging

  Optical imaging beyond the diffraction limit of light is revolutionizing sample analysis in the biological and physical sciences. Here Nature Photonics details the fundamental physics, the different approaches and the applications where super–resolution imaging can be of help.

  Nature Photonics (01 July 2009)

• Super-resolution Microscopy

  Fluorescence microscopy is acquiring new capabilities as methodological developments allow it to break the diffraction limit—a barrier that until recently prevented light microscopy from being used to interrogate details of cellular function beyond the resolving power of conventional light microscopy.

  Nature Methods (17 December 2008)

• Nanoscopy with more than 100,000 'doughnuts'

  Andriy Chmyrov, Jan Keller, Tim Grotjohann, Michael Ratz, Elisa d'Este, Stefan Jakobs, Christian Eggeling & Stefan W Hell.

  Nature Methods (07 July 2013)

• Diffraction-unlimited all-optical imaging and writing with a photochromic GFP.

  Tim Grotjohann, Ilaria Testa, Marcel Leutenegger, Hannes Bock, Nicolai T. Urban, Flavie Lavoie-Cardinal, Katrin I. Willig, Christian Eggeling, Stefan Jakobs & Stefan W. Hell.

  Nature (11 September 2011)

• A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching

  Tanja Brakemann, Andre C Stiel, Gert Weber, Martin Andresen, Ilaria Testa, Tim Grotjohann, Marcel Leutenegger, Uwe Plessmann, Henning Urlaub, Christian Eggeling, Markus C Wahl, Stefan W Hell & Stefan Jakobs.

  Nature Biotechnology (11 September 2011)

• Sharper low-power STED nanoscopy by time gating

  Giuseppe Vicidomini, Gael Moneron, Kyu Y Han, Volker Westphal, Haisen Ta, Matthias Reuss, Johann Engelhardt,Christian Eggeling & Stefan W Hell.

  Nature Methods (05 June 2011)

• Watching conformational- and photodynamics of single fluorescent proteins in solution

  Randall H. Goldsmith & W. E. Moerner.

  Nature Chemistry (31 January 2010)

• Diffraction-unlimited three-dimensional optical nanoscopy with opposing lenses

  Stefan W. Hell, Roman Schmidt1 & Alexander Egner.

  Nature Photonics (29 June 2009)

• STED microscopy reveals crystal colour centres with nanometric resolution

  Eva Rittweger, Kyu Young Han, Scott E. Irvine, Christian Eggeling & Stefan W. Hell.

  Nature Photonics (22 February 2009)

• Direct observation of the nanoscale dynamics of membrane lipids in a living cell

  Christian Eggeling, Christian Ringemann, Rebecca Medda, Günter Schwarzmann, Konrad Sandhoff, Svetlana Polyakova, Vladimir N. Belov, Birka Hein, Claas von Middendorff, Andreas Schönle & Stefan W. Hell.

  Nature (21 December 2008)

• Super-resolution imaging in live Caulobacter crescentus cells using photoswitchable EYFP

  Julie S Biteen, Michael A Thompson, Nicole K Tselentis, Grant R Bowman, Lucy Shapiro & W E Moerner.

  Nature Methods (15 September 2008)

• Spherical nanosized focal spot unravels the interior of cells

  Roman Schmidt, Christian A Wurm, Stefan Jakobs, Johann Engelhardt, Alexander Egner & Stefan W Hell.

  Nature Methods (18 May 2008)

• Live-cell photoactivated localization microscopy of nanoscale adhesion dynamics

  Hari Shroff, Catherine G Galbraith, James A Galbraith & Eric Betzig.

  Nature Methods (13 April 2008)

• High-density mapping of single-molecule trajectories with photoactivated localization microscopy

  Suliana Manley, Jennifer M Gillette, George H Patterson, Hari Shroff, Harald F Hess, Eric Betzig & Jennifer Lippincott-Schwartz.

  Nature Methods (13 January 2008)

• Photoswitchable fluorescent proteins enable monochromatic multilabel imaging and dual color fluorescence nanoscopy

  Martin Andresen, Andre C Stiel, Jonas Fölling, Dirk Wenzel, Andreas Schönle, Alexander Egner, Christian Eggeling, Stefan W Hell & Stefan Jakobs.

  Nature Biotechnology (24 August 2008)

• Fluorescence nanoscopy goes multicolor

  Andreas Schönle & Stefan W Hell.

  Nature Biotechnology (01 November 2007)

• STED microscopy with continuous wave beams

  Katrin I Willig, Benjamin Harke, Rebecca Medda & Stefan W Hell.

  Nature Methods (21 October 2007)

• STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis

  Katrin I. Willig, Silvio O. Rizzoli, Volker Westphal, Reinhard Jahn & Stefan W. Hell.

  Nature (13 April 2006)

• Nanoscale resolution in GFP-based microscopy

  Katrin I Willig, Robert R Kellner, Rebecca Medda, Birka Hein, Stefan Jakobs & Stefan W Hell.

  Nature Methods (23 August 2006)

• Immunofluorescence stimulated emission depletion microscopy

  Marcus Dyba, Stefan Jakobs & Stefan W Hell.

  Nature Biotechnology (19 October 2003)

• Single photons on demand from a single molecule at room temperature.

  B. Lounis & W. E. Moerner.

  Nature (28 September 2000)

Источник: http://www.nature.com/news/2014chemistrynobel-1.16160?WT.mc_id=GOP_NATURE_1410_NOBELCHEMSPEC_PORTFOLIO