Объявления: Литература

Спецвыпуск Nature 2014 NOBEL PRIZE IN PHYSIOLOGY OR MEDICINE

How do we know where we are, where we went and how we can reach our next destination? These routine mental operations all require an internal map of our surroundings that contains all the places we experienced and the multiple paths that we took to go from one place to another.

The so-called place and grid cells are two of the major neuron types that function as elementary parts in the brain’s positioning system. A place cell becomes active only in a particular location or near a particular landmark in the environment, whereas a grid cell’s activity peaks in multiple, equidistant places to form a geometric pattern akin to that formed by the intersections of a grid on a city map. This year’s Nobel prize was shared by John O’Keefe for his discovery of place cells and jointly by May-Britt and Edvard Moser for their discovery of grid cells. By supporting the sense of space, place and grid cells also enable mental projections into the future and the past, where events take place in specific spatial contexts.

In celebration, NPG is making available a range of articles from its journal archives that capture and reflect their remarkable achievements. Due to their impact and importance the research articles in the Highlights section will be free to access for a month.

HIGHLIGHTS

• Nobel prize for decoding brain’s sense of place

  Discoverers of brain’s navigation system get physiology Nobel.

  Nature (06 October 2014)

• Neuroscience: Brains of Norway

  Nobel prizewinners May-Britt Moser and Edvard Moser have spent a career together near the Arctic Circle exploring how our brains know where we are.

  Nature (06 October 2014)

• Neurons on border patrol

  The limits imposed by walls and trenches are recognized by special brain cells.

  Nature (18 December 2008)

• Grid cells and cortical representation

  Edvard I. Moser, Yasser Roudi, Menno P. Witter, Clifford Kentros, Tobias Bonhoeffer & May-Britt Moser.

  Nature Reviews Neuroscience (11 June 2014)

• Memory, navigation and theta rhythm in the hippocampal-entorhinal system

  György Buzsáki & Edvard I Moser.

  Nature Neuroscience (28 January 2013)

• Place navigation impaired in rats with hippocampal lesions

  R. G. M. Morris, P. Garrud, J. N. P. Rawlins & J. O'Keefe.

  Nature (24 June 1982)

• Microstructure of a spatial map in the entorhinal cortex

  Torkel Hafting, Marianne Fyhn, Sturla Molden, May-Britt Moser & Edvard I. Moser.

  Nature (19 June 2005)

LIBRARY

• Functional organization of the hippocampal longitudinal axis

  Bryan A. Strange, Menno P. Witter, Ed S. Lein & Edvard I. Moser.

  Nature Reviews Neuroscience (19 September 2014)

• Coordination of entorhinal–hippocampal ensemble activity during associative learning

  Kei M. Igarashi, Li Lu, Laura L. Colgin, May-Britt Moser & Edvard I. Moser.

  Nature (16 April 2014)

• Grid cells require excitatory drive from the hippocampus

  Tora Bonnevie, Benjamin Dunn, Marianne Fyhn, Torkel Hafting, Dori Derdikman, John L Kubie, Yasser Roudi, Edvard I Moser
  & May-Britt Moser.

  Nature Neuroscience (20 January 2013)

• Recurrent inhibitory circuitry as a mechanism for grid formation

  Jonathan J Couey, Aree Witoelar, Sheng-Jia Zhang, Kang Zheng, Jing Ye, Benjamin Dunn, Rafal Czajkowski, May-Britt Moser, Edvard I Moser, Yasser Roudi & Menno P Witter.

  Nature Neuroscience (20 January 2013)

• Impaired hippocampal rate coding after lesions of the lateral entorhinal cortex

  Li Lu, Jill K Leutgeb, Albert Tsao, Espen J Henriksen, Stefan Leutgeb, Carol A Barnes, Menno P Witter, May-Britt Moser & Edvard I Moser.

  Nature Neuroscience (14 July 2013)

• The entorhinal grid map is discretized

  Hanne Stensola, Tor Stensola, Trygve Solstad, Kristian Frøland, May-Britt Moser & Edvard I. Moser.

  Nature (05 December 2012)

• Theta-paced flickering between place-cell maps in the hippocampus

  Karel Jezek, Espen J. Henriksen, Alessandro Treves,Edvard I. Moser & May-Britt Moser.

  Nature (28 September 2011)

• Grid cells in pre- and parasubiculum

  Charlotte N Boccara, Francesca Sargolini, Veslemøy Hult Thoresen, Trygve Solstad, Menno P Witter, Edvard I Moser & May-Britt Moser.

  Nature Neuroscience (25 July 2010)

• Fragmentation of grid cell maps in a multicompartment environment

  Dori Derdikman, Jonathan R Whitlock, Albert Tsao, Marianne Fyhn, Torkel Hafting, May-Britt Moser & Edvard I Moser.

  Nature Neuroscience (13 September 2009)

• Frequency of gamma oscillations routes flow of information in the hippocampus

  Laura Lee Colgin, Tobias Denninger, Marianne Fyhn, Torkel Hafting, Tora Bonnevie, Ole Jensen, May-Britt Moser & Edvard I. Moser.

  Nature (19 November 2009)

• Hippocampus-independent phase precession in entorhinal grid cells

  Torkel Hafting, Marianne Fyhn, Tora Bonnevie, May-Britt Moser & Edvard I. Moser.

  Nature (14 May 2008)

• Hippocampal remapping and grid realignment in entorhinal cortex

  Marianne Fyhn, Torkel Hafting, Alessandro Treves, May-Britt Moser and Edvard I. Moser.

  Nature (25 February 2007)

• Path integration and the neural basis of the 'cognitive map'

  Bruce L. McNaughton, Francesco P. Battaglia, Ole Jensen, Edvard I Moser & May-Britt Moser.

  Nature Reviews Neuroscience (01 August 2006)

• Independent rate and temporal coding in hippocampal pyramidal cells

  John Huxter, Neil Burgess & John O'Keefe.

  Nature (15 September 2003)

• Long-term plasticity in hippocampal place-cell representation of environmental geometry

  Colin Lever, Tom Wills, Francesca Cacucci, Neil Burgess & John O'Keefe.

  Nature (07 January 2002)

• Geometric determinants of the place fields of hippocampal neurons

  John O'Keefe & Neil Burgess.

  Nature (30 May 1996)

Истчоник: http://www.nature.com/news/2014medicinenobel-1.16167?WT.mc_id=GOP_NATURE_1410_NOBELMEDSPEC_PORTFOLIO