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"Физика и клетка" (Physics and the Cell) все статьи в свободном доступе до 31 марта 2011 г
Применение физических методов исследований помогает при изучении биологических объектов - клеток, в том числе, их поведение и функции. И численные методы, и различные эксперименты по изучению свойств материалов, широко используемые во многих физических лабораториях, оказываются полезными инструментами в биологии тоже, при изучении таких объектов, как живые клетки.
СодержаниеNature Physics Insight – Physics and the Cell:
Editorial
Physics and the cell - - p725
David Gevaux
Perspective
Physics challenged by cells - pp726 - 729
Ana-Sunčana Smith
Cells are the building blocks of life. Ideas traditionally applied to physical problems are now helping to unravel their complex mysteries.
Commentary
Are biomechanical changes necessary for tumour progression? - pp730 - 732
Anatol Fritsch, Michael Höckel, Tobias Kiessling, Kenechukwu David Nnetu, Franziska Wetzel, Mareike Zink & Josef A. Käs
Cell biophysics sheds some new light on cancer by approaching this complex problem from a materials science perspective.
Review Articles
Physical virology - pp733 - 743
W. H. Roos, R. Bruinsma & G. J. L. Wuite
Viruses are protected by a protein shell known as a capsid. The mechanical properties of capsids have been the focus of intense experimental and theoretical investigation with the hope that a better understanding will open the door to new medical treatments and applications in biotechnology.
X-ray imaging beyond the limits - pp744 - 750
Dante R. Chialvo
Is the brain on the edge of criticality? Understanding the inner workings of the brain is a task made difficult by the number of elements involved: a hundred billion neurons and a hundred trillion synapses. Viewing the brain in terms of collective dynamics is one approach now yielding some insight.
Challenges in protein-folding simulations - pp751 - 758
Peter L. Freddolino, Christopher B. Harrison, Yanxin Liu & Klaus Schulten
A protein's shape is crucial for fulfilling its function within a cell. This Review discusses how molecular dynamics simulations have given us insight into the processes that turn a linear chain of amino acids into a unique three-dimensional protein.